Cross-group comparisons of Z-scores Lead Investigator: Zhixuan Shao Institution : NACC Peking University E-Mail : shaozhixuansh@pku.edu.cn Proposal ID : 1090 Proposal Description: We want to improve the method for establishing cognitive norms from the NACC dataset, and apply the improved method to cross-group comparisons which may help indicate levels of cognitive deficiency. Our objectives include: 2 propose a quatile regression model that will improve the results from the neuropsychological norms paper (Weintraub et al. 2018) on the webiste 3 apply the improved method to cross-group comparisons. Three different groups: normal, MCI, AD. For these reasons, we request for the latest dataset of normal controls, MCI and dementia participants. Each dataset should include: 1 demographics and characteristics including education, sex, race, age, etc. as covariates X 2 neuropsychological tests, as outcomes Y